Synthesis of Pyrazines from Rhodium-Catalyzed Reaction of 2H-Azirines with N-Sulfonyl 1,2,3-Triazoles

Ryu, Taekyu; Baek, Yonghyeon; Lee, Phil Ho

doi:10.1021/acs.joc.5b00036

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Synthesis of Pyrazines from Rhodium-Catalyzed Reaction of 2H-Azirines with N-Sulfonyl 1,2,3-Triazoles

Ryu, Taekyu;
Baek, Yonghyeon;
Lee, Phil Ho

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WEB OF SCIENCE

102

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SCOPUS

108

초록

An efficient synthetic route to a wide range of trisubstituted pyrazines is developed from Rh-catalyzed reaction of 2H-azirines with N-sulfonyl-1,2,3-triazoles through the elimination of nitrogen molecule and arylsulfinic acid. The present reaction proceeds through formation of in situ generated dihydropyrazines.

키워드

TERMINAL ALKYNES; H INSERTION; TRANSANNULATION; AZIDES; ANNULATION; TRIAZOLES; PYRROLES; 1-SULFONYL-1,2,3-TRIAZOLES; CYCLOADDITION; CONVERSION

제목: Synthesis of Pyrazines from Rhodium-Catalyzed Reaction of 2H-Azirines with N-Sulfonyl 1,2,3-Triazoles

저자: Ryu, Taekyu; Baek, Yonghyeon; Lee, Phil Ho

DOI: 10.1021/acs.joc.5b00036

발행일: 2015-02-20

유형: Article

저널명: The Journal of Organic Chemistry

권: 80

호: 4

페이지: 2376 ~ 2383