3-Hydroxypropionic acid의 생산 경로와 이를 생산하는 미생물 균주

A Biosynthetic Pathway for 3-hydroxypropionic acid Production in Various Microbial Strains

초록

This review provides information on the characteristics and synthetic pathways of 3-hydroxypropionic acid (3- HP), a raw material for biodegradable plastics. The synthetic pathways of 3-HP are divided into three main routes: the malonyl- CoA pathway, the β-alanine pathway, and the glycerol pathway. Each synthetic route is comparatively analyzed in terms of mechanism, efficiency, and economic feasibility. Consequently, 3-HP can be effectively produced as a biodegradable plastic through various synthetic pathways and efficient microbial strains. This review provides fundamental information on the mechanisms of 3-HP and its future research applications, emphasizing its potential to play a significant role as a key raw material for non-petroleum-based biodegradable plastics, which are environmentally friendly and economically advantageous.

키워드

3-hydroxypropionic acid; malonyl CoA; β-alanine; glycerol
제목
3-Hydroxypropionic acid의 생산 경로와 이를 생산하는 미생물 균주
제목 (타언어)
A Biosynthetic Pathway for 3-hydroxypropionic acid Production in Various Microbial Strains
저자
최보라; 최수영; 김현욱; 하석진
DOI
10.7841/ksbbj.2025.40.1.53
발행일
2025-03
유형
Y
저널명
Korean Society for Biotechnology and Bioengineering Journal
권
40
호
1
페이지
53 ~ 58