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초록
Coumarins were obtained from the condensation of electron-rich arenes with allenes in the presence of TfOH in good yield. Depending on the substituent pattern of allenes employed, the general synthetic method of 4-substituted and 3,4-disubstituted 3-arylcoumarins has been developed. Readily available allenes were employed as the three-carbon atom sources constituting the coumarin skeleton.
키워드
CROSS-COUPLING REACTIONS; CATALYZED INTRAMOLECULAR HYDROARYLATION; ETHYL 2-ARYL 2,3-ALKADIENOATES; ONE-POT; 3,4-DISUBSTITUTED COUMARINS; EFFICIENT ROUTE; CARBONYLATIVE ANNULATION; 4-SUBSTITUTED COUMARINS; PECHMANN CONDENSATION; INTERNAL ALKYNES
- 제목
- Synthesis of Substituted Coumarins via Bronsted Acid Mediated Condensation of Allenes with Substituted Phenols or Anisoles
- 저자
- Kim, Sundae; Kang, Dongjin; Lee, Chang-Hee; Lee, Phil Ho
- 발행일
- 2012-08-03
- 유형
- Article
- 권
- 77
- 호
- 15
- 페이지
- 6530 ~ 6537