Synthesis of 2-Alkyl- and Ary1-3-ethoxycarbony1-2,5-dihydrofurans through Gold-Catalyzed Intramolecular Hydroalkoxylation

Eom, Dahan; Kang, Dongjin; Lee, Phil Ho

doi:10.1021/jo101474s

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Synthesis of 2-Alkyl- and Ary1-3-ethoxycarbony1-2,5-dihydrofurans through Gold-Catalyzed Intramolecular Hydroalkoxylation

Eom, Dahan;
Kang, Dongjin;
Lee, Phil Ho

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WEB OF SCIENCE

51

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SCOPUS

59

초록

Treatment of a wide range of functionalized hydroxyallenic esters with 5 mol % Ph3PAuCl and 5 mol % AgOTf in CH2Cl2 at 25 degrees C for l h produced selectively 2-alkyl- and aryl-3-ethoxycarbony1-2,5-dihydrofurans in good to excellent yield through intramolecular hydroalkoxylation by a 5-endo mode.

키워드

RING-CLOSING METATHESIS; COUPLING-CYCLIZATION REACTION; EFFICIENT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; 2,5-DIHYDROFURAN DERIVATIVES; ALLENIC ALCOHOLS; ALLYLIC HALIDES; ALDEHYDES; CYCLOISOMERIZATION; DIHYDROFURANS

제목: Synthesis of 2-Alkyl- and Ary1-3-ethoxycarbony1-2,5-dihydrofurans through Gold-Catalyzed Intramolecular Hydroalkoxylation

저자: Eom, Dahan; Kang, Dongjin; Lee, Phil Ho

DOI: 10.1021/jo101474s

발행일: 2010-11-05

유형: Article

저널명: The Journal of Organic Chemistry

권: 75

호: 21

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