Enhancement of antioxidant activities of Codonopsis lanceolata and fermented Codonopsis lanceolata by ultra high pressure extraction

초록

This study was designed to evaluate antioxidant activity of low-quality Codonopsis lanceolata treated byfermentation process followed by hydraulic high pressure extraction. C. lanceolata was subjected to 5,000 barfor 30 min at 25°C. The highest phenolics content was observed in the combined treatment of fermentationand high pressure extraction (35.11 mg/100 g), followed by high pressure extraction alone (14.78 mg/100 g)and conventional extraction (14.56 mg/100 g). The content of flavonoids followed the similar pattern as thatof total phenolics, showing 280.86 mg/100 g of C. lanceolata treated by the combined fermentation with highpressure extraction whereas 193.05 mg/100 g of C. lanceolata treated by the conventional extraction. The DPPHscavenging activity was 69.32% at 0.6 mg/mL of C. lanceolata treated by the combined process, while the DPPHscavenging activities of C. lanceolata treated by high pressure extraction alone and the conventional extractionwere 60.35% and 30.92%, respectively. The highest reducing power of C. lanceolata extract (1.0 mg/mL) wasobserved at the combined treatment (0.926), followed by high pressure extraction alone (0.881) and theconventional extraction (0.733). The combination of fermentation with high pressure extraction significantlyincreased the contents of phenolics and flavonoids and also enhanced the antioxidant activity. Therefore, thecombined application of fermentation and high pressure extraction can be an alternative technique for theextraction of C. lanceolata. These results provide useful information for enhancing biological properties oflow-quality C. lanceolata.

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