A facile green synthesis of multifunctional silver nanoparticles using Paeonia suffruticosa seed extracts

초록

In this work, peony seed cake extract (PSCE) was utilized to synthesize silver nanoparticles (Ag NPs) for antibacterial, antioxidant, and cytotoxicity applications. Characterization of the PSCE-Ag NPs showed that they had a spherical form, with an average size of 105.6 & PLUSMN; 3.49 nm and a zeta potential of -41.8 & PLUSMN; 12.6 mV. PSCE-Ag NPs significantly inhbited the growth and biofilm formation of Bacillus cereus, Staphylococcus aureus, Escherichia coli, and Salmonella enterica. Further, PSCE-Ag NPs demonstrated potent 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS+) free radical scavenging ability. Additionally, PSCE-Ag NPs had no toxic effects on erythrocytes, egg-chorioallantoic membrane, and human embryonic kidney cells (HEK293) while drastically reducing the growth of breast cancer cells (BT474).

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