Synthesis of N-Imidoyl and N-Oxoimidoyl Sulfoximines from 1-Alkynes, N-Sulfonyl Azides, and Sulfoximines

Choi, Wonseok; Kim, Jaeeun; Ryu, Taekyu; Kim, Ki-Bbeum; Lee, Phil Ho

doi:10.1021/acs.orglett.5b01553

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Synthesis of N-Imidoyl and N-Oxoimidoyl Sulfoximines from 1-Alkynes, N-Sulfonyl Azides, and Sulfoximines

Choi, Wonseok;
Kim, Jaeeun;
Ryu, Taekyu;
Kim, Ki-Bbeum;
Lee, Phil Ho

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WEB OF SCIENCE

33

Citations

SCOPUS

33

초록

N-Imidoylation of sulfoximines is developed from a Cu-catalyzed three-component reaction from 1-alkynes, N-sulfonyl azides, and sulfoximines in THF at room temperature under air. In addition, N-oxoimidoylation of sulfoximines is accessed from a Cu-catalyzed three-component reaction from 1-alkynes, N-sulfonyl azides, and sulfoximines in THF at room temperature followed by a Cu-catalyzed oxidative reaction at 50 degrees C under air, producing N-oxoimidoyl sulfoximines.

키워드

ONE-POT SYNTHESIS; FACILE ACCESS; ARYL IODIDES; FLUORINATED SULFOXIMINES; ASYMMETRIC CATALYSIS; 3-COMPONENT REACTION; ARYLATION; AMIDINES; BROMIDES; SULFILIMINES

제목: Synthesis of N-Imidoyl and N-Oxoimidoyl Sulfoximines from 1-Alkynes, N-Sulfonyl Azides, and Sulfoximines

저자: Choi, Wonseok; Kim, Jaeeun; Ryu, Taekyu; Kim, Ki-Bbeum; Lee, Phil Ho

DOI: 10.1021/acs.orglett.5b01553

발행일: 2015-07-03

유형: Article

저널명: Organic Letters

권: 17

호: 13

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