EpCAM and CD24 specific EVRNA analysis for ovarian cancer diagnosis

Kim, Yejin; Hyun, Da Han; Lee, Yoon Hee; Lim, Woojeong; Lee, Hoyeon; Lee, Soyeon; Jang, Hyeon-Ki; Lim, Joohyun; Hong, Dae Gy; Park, Jun Seok; Park, Soo Yeun; Park, Jongmin

doi:10.1002/bkcs.70041

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EpCAM and CD24 specific EVRNA analysis for ovarian cancer diagnosis

Kim, Yejin;
Hyun, Da Han;
Lee, Yoon Hee;
Lim, Woojeong;
Lee, Hoyeon;
... Jang, Hyeon-Ki;
... Lim, Joohyun;
... Park, Jongmin;
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초록

Extracellular vesicles (EVs) are recently emerged as biomarkers for cancer diagnosis. RNA in EV specifically has drawn attention for its high stability and accuracy for early cancer diagnosis. However, analysis of EV RNA in plasma for cancer diagnosis often can be limited by a low population of cancer-derived EVs in the plasma samples. Herein, we developed a sensitive EV RNA analysis technique with protein-specific EV enrichment for accurate ovarian cancer diagnosis.

키워드

extracellular vesicle; immunomagnetic enrichment; miRNA; ovarian cancer; PROMISING BIOMARKERS; LIQUID-BIOPSY; RNA; PROTEINS; EXOSOMES; MIRNAS

제목: EpCAM and CD24 specific EVRNA analysis for ovarian cancer diagnosis

저자: Kim, Yejin; Hyun, Da Han; Lee, Yoon Hee; Lim, Woojeong; Lee, Hoyeon; Lee, Soyeon; Jang, Hyeon-Ki; Lim, Joohyun; Hong, Dae Gy; Park, Jun Seok; Park, Soo Yeun; Park, Jongmin

DOI: 10.1002/bkcs.70041

발행일: 2025-07

유형: Article

저널명: Bulletin of the Korean Chemical Society

권: 46

호: 7

페이지: 673 ~ 679