Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum

Song, YS; Kim, SH; Sa, JH; Jin, C; Lim, CJ; Park, EH

doi:10.1016/j.jep.2003.09.006

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Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum

Song, YS;
Kim, SH;
Sa, JH;
Jin, C;
Lim, CJ;
외 1명

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WEB OF SCIENCE

65

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SCOPUS

80

초록

Fresh fruit bodies of Ganoderma lucidum were extracted with 70%. ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

키워드

ganoderma lucidum; anti-angiogenic activity; nitric oxide; folk medicine; ANTIHERPETIC ACTIVITIES; L-ARGININE; SYNTHASE; COMBINATIONS; SUBSTANCES; GROWTH

제목: Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum

저자: Song, YS; Kim, SH; Sa, JH; Jin, C; Lim, CJ; Park, EH

DOI: 10.1016/j.jep.2003.09.006

발행일: 2004-01

유형: Article

저널명: Journal of Ethnopharmacology

권: 90

호: 1

페이지: 17 ~ 20