Plasmodium ovale curtisi and Plasmodium ovale wallikeri in Chinese travelers: Prevalence of novel genotypes of circumsporozoite protein in the African continent

Fu, Feng; Ahmed, Md Atique; Xu, Simin; Xu, Sui; Han, Jin-Hee; Liu, Qianyan; Chen, Jing; Zhu, Guoding; Zhou, Huayun; Cao, Jun; Han, Eun-Taek

doi:10.1016/j.meegid.2019.02.008

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Plasmodium ovale curtisi and Plasmodium ovale wallikeri in Chinese travelers: Prevalence of novel genotypes of circumsporozoite protein in the African continent

Fu, Feng;
Ahmed, Md Atique;
Xu, Simin;
Xu, Sui;
Han, Jin-Hee;
... Han, Eun-Taek;
외 5명

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초록

Imported malaria due to Plasmodium ovale curtisi and P. ovale wallikeri infections from African countries has increased recently (2011-2014) in Chinese travelers. We report novel genotypes, their prevalence and the predominant haplotypes of P. ovale curtisi and P. ovale wallikeri circumsporozoite protein (CSP) from 20 African countries in Chinese travelers. These genotypes should be considered while designing a CSP-based vaccine against P. ovale malaria.

키워드

Plasmodium ovale; Circumsporozoite protein; Genotypes; Africa; Imported case; China; GENETIC DIVERSITY; FALCIPARUM; EFFICACY; PARASITE; MALARIAE; ANTIGEN; VACCINE

제목: Plasmodium ovale curtisi and Plasmodium ovale wallikeri in Chinese travelers: Prevalence of novel genotypes of circumsporozoite protein in the African continent

저자: Fu, Feng; Ahmed, Md Atique; Xu, Simin; Xu, Sui; Han, Jin-Hee; Liu, Qianyan; Chen, Jing; Zhu, Guoding; Zhou, Huayun; Cao, Jun; Han, Eun-Taek

DOI: 10.1016/j.meegid.2019.02.008

발행일: 2019-06

유형: Article

저널명: Infection, Genetics and Evolution

권: 70

페이지: 9 ~ 14