Preload control of the increased outflow of a dual pulsatile extracorporeal membrane oxygenator

초록

An improved pulsatile extracorporeal membrane oxygenation (ECMO) device is needed to reduce the high risk of complications associated with existing ECMO devices, due to continuous blood outflow (which reduces blood perfusion) and a complex structure that makes setup and management difficult. This study introduces a new pulsatile ECMO device to maintain sufficient pulsatility (an "energy equivalent pressure increment" [EEPI] of at least 20 %) and simplify the structure of the pulsatile pump by removing artificial valves and complex actuators. The hemodynamic characteristics and pulsatility of the proposed pulsatile ECMO device were evaluated in-vitro using a MOCK system. Although the pulsatile ECMO device has the same dual pumping structure as existing pulsatile ECMOs, the newly applied preload control mechanism increases the outflow of the proposed pulsatile ECMO compared to the previous device.

키워드