Ligand-controlled regiodivergent direct arylation of indoles via oxidative boron Heck reaction

  • Yang, Yo-Sep; 
  • Lee, Sangmin; 
  • Son, Seung Hwan; 
  • Yoo, Hyung-Seok; 
  • Jang, Yoon Hu; 
  • 외 4명
Citations

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15
Citations

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15

초록

Ligand-controlled direct arylation of indoles via Pd(ii) catalyzed oxidative boron Heck reaction under aerobic conditions is reported. This methodology provides a regiodivergent route for C2 or C3 aryl indoles in a protection free and acid/base free manner.

키워드

C-H ARYLATION; CATALYST-CONTROLLED REGIOSELECTIVITY; DIRECT C-2 ARYLATION; ROOM-TEMPERATURE; FREE (NH)-INDOLES; FUNCTIONALIZATION; ACTIVATION
제목
Ligand-controlled regiodivergent direct arylation of indoles via oxidative boron Heck reaction
저자
Yang, Yo-Sep; Lee, Sangmin; Son, Seung Hwan; Yoo, Hyung-Seok; Jang, Yoon Hu; Shin, Jeong-Won; Won, Hyuck-Jae; Sim, Jaehoon; Kim, Nam-Jung
DOI
10.1039/d2qo01326f
발행일
2022-10-25
유형
Article
저널명
Organic Chemistry Frontiers
권
9
호
21
페이지
5906 ~ 5911