The Effects of Psychosocial Interventions on Anxiety and Depression in Siblings of Children with Cancer: A Systematic Review and Meta-Analysis

초록

This systematic review and meta-analysis evaluated the effects of psychosocial interventions for siblings of children with cancer. A total of 538 studies were screened, and 14 were ultimately included. The pooled analysis of 12 studies addressing anxiety demonstrated a moderate reduction effect (SMD = –0.52, 95% CI: –0.68 to –0.35, p < .001; I² = 0%), with significant benefits observed in educational and supportive programs, CBT-based interventions, camp programs, interventions delivered in 3–9 sessions, and those conducted in family- or group-based formats. In contrast, the pooled effect from seven studies addressing depression was not statistically significant (SMD = –0.74, p = .08; I² = 93%), showing substantial heterogeneity across studies. These findings suggest that structured psychosocial interventions are effective in alleviating anxiety among siblings of children with cancer, whereas the effects on depression remain inconsistent. Further randomized controlled trials and studies examining long-term outcomes are warranted.

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