Polymer Nanohybrid-Based Smart Platforms for Controlled Delivery and Wound Management

초록

Polymer nanohybrid-based smart materials are considered promising platforms for targeted drug delivery and wound healing management. These systems have advantages over conventional systems where precise drug delivery and improved wound healing are required. Synthetic and naturally derived polymers with different nanomaterials are often utilized to develop these platforms. Different approaches, including electrospinning and three-dimensional printing (3D), are frequently explored to fabricate smart platforms. These platforms may be in form of patches, 3D-printed structures, or soft nano-robots. The biological activities of these promising platforms are profoundly affected by different factors, including pH, the temperature of local environments, external stimuli such as electric and magnetic fields, and the physicochemical properties of the developed platforms. The present chapter briefly discussed different polymer nanohybrid-based smart platforms for controlled drug release and wound healing applications. The materials (polymers and nanomaterials) used to prepare the smart platforms were highlighted. The effects of different stimuli (pH, temperature, electric and magnetic fields) on the biological activities of these platforms were also discussed. We anticipate that the present chapter may provide important information about smart polymeric platforms for controlled cargo delivery and wound healing management. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.

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