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Syntheses and anti-MRSA activities of the C3 analogs of mansonone F, a potent anti-bacterial sesquiterpenoid: insights into its structural requirements for anti-MRSA activity
- Shin, DY;
- Kim, SN;
- Chae, JH;
- Hyun, SS;
- Seo, SY;
- ... Kim, SH;
- 외 6명
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Syntheses and excellent anti-MRSA activities of the mansonone F analogs are reported. In addition, the minimal structural requirements for its anti-MRSA activities as well as its structure-activity relationship including the C3 substituents effects on anti-MRSA activity are also described. In particular, this study revealed that both ortho-quinone and tricyclic systems of mansonone F are essential for anti-MRSA activities. (C) 2004 Elsevier Ltd. All rights reserved.
키워드
mansonone F; anti-MRSA
- 제목
- Syntheses and anti-MRSA activities of the C3 analogs of mansonone F, a potent anti-bacterial sesquiterpenoid: insights into its structural requirements for anti-MRSA activity
- 저자
- Shin, DY; Kim, SN; Chae, JH; Hyun, SS; Seo, SY; Lee, YS; Lee, KO; Kim, SH; Lee, YS; Jeong, JM; Choi, NS; Suh, YG
- 발행일
- 2004-09-06
- 유형
- Article
- 권
- 14
- 호
- 17
- 페이지
- 4519 ~ 4523