상세 보기
Phenolic Compounds from Caesalpinia sappan Heartwood and Their Anti-inflammatory Activity
- Cuong, To Dao;
- Tran Manh Hung;
- Kim, Jin Cheol;
- Kim, Eun Hee;
- Woo, Mi Hee;
- ... Lee, Jeong Hyung;
- 외 2명
Citations
WEB OF SCIENCE
67Citations
SCOPUS
80초록
Four new phenolic compounds, caesalpiniaphenols A-D (1-4), together with eight known compounds were isolated from Caesalpinia sappan heartwood. The chemical structures were established mainly by NMR, MS, ECD, and Mosher's method. Compounds 4, 5, and 7 showed weak inhibitory activity against the LPS-induced NO production in macrophage RAW264.7 cells with IC50 values of 12.2, 3.5, and 5.7 mu M, respectively.
키워드
NITRIC-OXIDE SYNTHASE; AROMATIC-COMPOUNDS; ENDOTHELIAL-CELLS; HOMOISOFLAVONOIDS; CONSTITUENTS; BRAZILIN; EXPRESSION; INJURY; LIGNUM; LIPOPOLYSACCHARIDE
- 제목
- Phenolic Compounds from Caesalpinia sappan Heartwood and Their Anti-inflammatory Activity
- 저자
- Cuong, To Dao; Tran Manh Hung; Kim, Jin Cheol; Kim, Eun Hee; Woo, Mi Hee; Choi, Jae Sue; Lee, Jeong Hyung; Min, Byung Sun
- 발행일
- 2012-12
- 유형
- Article
- 권
- 75
- 호
- 12
- 페이지
- 2069 ~ 2075
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 7 페이지
- ISSN
- E 1520-6025
P 0163-3864