Synthetic Method for the Preparation of 2-Aminomethyl-1,3-diene Derivatives through Indium-Mediated 1,3-Butadien-2-ylation of Imines

Seomoon, Dong; Jaemyung, A.; Lee, Phil Ho

doi:10.1021/ol9005213

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Synthetic Method for the Preparation of 2-Aminomethyl-1,3-diene Derivatives through Indium-Mediated 1,3-Butadien-2-ylation of Imines

Seomoon, Dong;
Jaemyung, A.;
Lee, Phil Ho

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WEB OF SCIENCE

24

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SCOPUS

24

초록

An efficient method for the preparation of a variety of 2-aminomethyl-1,3-dienes was developed through the reaction of imines with organoindium reagent generated in situ from indium and 1,3-dibromo-2-butyne. Three-component reactions of aldehydes, amines, and organoindium reagents gave successful results in a one-pot process.

키워드

DIELS-ALDER REACTION; ASYMMETRIC-SYNTHESIS; AQUEOUS-MEDIA; ORGANOMETALLIC REACTIONS; DIASTEREOSELECTIVE ALLYLATION; AMINO-ACIDS; REAGENTS; PROPARGYLATION; SULFONIMINES; HYDRAZONE

제목: Synthetic Method for the Preparation of 2-Aminomethyl-1,3-diene Derivatives through Indium-Mediated 1,3-Butadien-2-ylation of Imines

저자: Seomoon, Dong; Jaemyung, A.; Lee, Phil Ho

DOI: 10.1021/ol9005213

발행일: 2009-06-04

유형: Article

저널명: Organic Letters

권: 11

호: 11

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