상세 보기
Iron-catalyzed indirect hydration of alkynes in presence of methanesulfonic acid
- Park, Jungmin;
- Yeon, Jihee;
- Lee, Phil Ho;
- Lee, Kooyeon
Citations
WEB OF SCIENCE
76Citations
SCOPUS
77초록
We have demonstrated that the FeCl2 center dot 4H(2)O and methanesulfonic acid systems show high reaction efficiency for the indirect hydration of various alkynes in DCE. The reaction proceeds under mild conditions to produce various ketones from alkynes. A mechanistic study of the reaction intermediates showed that the alkyne was readily converted into vinyl sulfonate corresponding to the addition of MsOH to the C-C triple bonds, which in turn was transformed to the ketone in the presence of MsOH. (C) 2013 Elsevier Ltd. All rights reserved.
키워드
Iron; Hydration; Alkynes; Ketones; Catalysis; ANTI-MARKOVNIKOV HYDRATION; HIGHLY EFFICIENT CATALYSTS; TERMINAL ALKYNES; REGIOSELECTIVE HYDRATION; ATOM ECONOMY; WATER; COMPLEXES; CHLORIDE; METAL; ACETYLENES
- 제목
- Iron-catalyzed indirect hydration of alkynes in presence of methanesulfonic acid
- 저자
- Park, Jungmin; Yeon, Jihee; Lee, Phil Ho; Lee, Kooyeon
- 발행일
- 2013-08-14
- 유형
- Article
- 권
- 54
- 호
- 33
- 페이지
- 4414 ~ 4417