α-Glucosidic hydroquinone derivatives from Viburnum erosum

Park, Jinyoung; Lee, Jiho; Jang, Hyeon Seok; Jeong, Birang; Choi, Seong Yeon; Kim, Juyeol; Kwon, Yong Soo; Yang, Heejung

doi:10.1016/j.phytochem.2021.112782

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α-Glucosidic hydroquinone derivatives from Viburnum erosum

Park, Jinyoung;
Lee, Jiho;
Jang, Hyeon Seok;
Jeong, Birang;
Choi, Seong Yeon;
... Kwon, Yong Soo;
... Yang, Heejung;
외 1명

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초록

Six undescribed compounds (1-6) were isolated from the leaves of Viburnum erosum along with four known compounds 7-10. The structures were determined by NMR and MS spectroscopic analyses, and their absolute configurations were established by chemical and spectroscopic methods. Compounds 1-6 were alpha-glucosidic hydroquinone derivatives with different linear monoterpenoid structures. Compounds 1-10 were also evaluated for their tyrosinase inhibitory activities, and 10 showed potent inhibition of tyrosinase enzyme with IC50 value of 37.9 mu M compared to 47.6 mu M of the positive control (beta-arbutin).

키워드

Viburnum erosum; Tyrosinase inhibition; beta-arbutin; CHEMICAL-CONSTITUENTS

제목: α-Glucosidic hydroquinone derivatives from Viburnum erosum

저자: Park, Jinyoung; Lee, Jiho; Jang, Hyeon Seok; Jeong, Birang; Choi, Seong Yeon; Kim, Juyeol; Kwon, Yong Soo; Yang, Heejung

DOI: 10.1016/j.phytochem.2021.112782

발행일: 2021-07

유형: Article

저널명: Phytochemistry

권: 187