The Understanding and Development of Acquiring of Nuclear Medicine Images: A Review of Past, Present and Future

초록

Using radioactive isotopes and non-sealed labeling compounds, the brain's mechanism of action could be analyzed from a molecular perspective using the characteristics of a positron emission tomography (PET) image, which could identify molecular changes in the region of interest in the human body in three dimensions. Similarly, magnetic resonance imaging (MRI) images provide high-resolution anatomical information to determine the activity of nerve cells that reflect the activity of brain neurotransmitters and receptors. After measuring the brain neurotransmitter through MRI images and the amount of Blood Oxygenation Level Dependent (BOLD) produced by receptors, certain areas of the brain could identify activation changes. The development of positron emission tomography-magnetic resonance imaging (PET-MRI) has been made to reflect the respective characteristics of PET and MRI images at the same time.

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