A Rh-catalyzed regio- and stereoselective route to enamides: benzamides as assembling reagents

초록

A new protocol for the synthesis of fully substituted enaminones has been achieved using a diverse range of benzamides and 1-sulfonyl-1,2,3- triazoles. Selective removal of the beta-amino moiety of the obtained alpha-amido-enaminones to form Z-enamides was also demonstrated thus improving the synthetic value of benzamides for structural diversities in a minimum number of synthetic steps.

키워드