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A New Dibenzofuran from the Barks of Sorbus commixta
- Choi, Seong Yeon;
- Jeong, Birang;
- Jang, Hyeon Seok;
- Lee, Jiho;
- Ko, Kiwon;
- ... Yang, Heejung;
- 외 3명
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10초록
A new dibenzofuran derivative, 1,2,4-trimethoxydibenzofuran-3,9-diol (7), was isolated from the ethyl acetate fraction of Sorbus commixta barks, along with six known compounds, lupeol (1), betulin (2), betulinic acid (3), ursolic acid (4), beta-sitosterol (5) and beta-pyrufuran (6). Their structures were determined by NMR spectroscopic analysis, including of H-1 and C-13 NMR, COSY, HSQC and HMBC spectra data. Cytotoxic activities of seven compounds were evaluated in five cancer cell lines, HEp-2, A549, MCF-7, PC -3 and SKOV-3 at the concentrations ranging from 10 to 100 mu M.
키워드
Sorbus commixta; triterpenes; dibenzofuran; 1,2,4-trimethoxydibenzofuran 3,9-diol; cytotoxicity; EXTRACT; RATS
- 제목
- A New Dibenzofuran from the Barks of Sorbus commixta
- 저자
- Choi, Seong Yeon; Jeong, Birang; Jang, Hyeon Seok; Lee, Jiho; Ko, Kiwon; Kim, Hyunha; Hong, Jua; Bae, Young Soo; Yang, Heejung
- 발행일
- 2018-03
- 유형
- Article
- 권
- 12
- 호
- 2
- 페이지
- 179 ~ 183
- 언어
- ENG
- 출판사
- ACG PUBLICATIONS
- 발행국가
- 튀르키예
- 분량
- 5 페이지
- ISSN
- P 1307-6167