상세 보기
초록
An efficient synthetic method of 1,4-dihydronaphthalenes having various alkyl groups on the 4-position and/or ethoxycarbonyl group on the 2-position through selective intramolecular Pt-catalyzed 6-endo cyclohydroarylation of ethyl 2-benzy1-2,3-alkadienoates was developed. The present method could be further extended to two-fold Pt-catalyzed 6-endo and 7-endo cyclizations.
키워드
METAL-AMMONIA REDUCTION; BIRCH REDUCTION; AROMATIC-COMPOUNDS; CYCLOISOMERIZATION REACTION; CYCLIZATION REACTION; ORGANIC-SYNTHESIS; NATURAL-PRODUCTS; 4+2 ANNULATION; INDOLES; ALKYNES
- 제목
- Platinum-Catalyzed Intramolecular Hydroarylation of Allenyl Arenes: Efficient Synthesis of 1,4-Dihydronaphthalenes
- 저자
- Mo, Juntae; Lee, Phil Ho
- 발행일
- 2010-06-04
- 유형
- Article
- 저널명
- Organic Letters
- 권
- 12
- 호
- 11
- 페이지
- 2570 ~ 2573