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초록
Ginsenoside Re (Re), a major ginsenoside of ginseng, enhanced the cornified cell envelope (CE) formation in HaCaT keratinocytes under normal conditions. In HaCaT keratinocytes, Re was also able to upregulate filaggrin protein and caspase-14 activity in a concentration-dependent manner. These findings reasonably imply that Re possesses a desirable property of improving skin barrier function.
키워드
ginsenoside Re; cornified cell envelope; filaggrin; caspase-14; HaCaT; ATOPIC-DERMATITIS; EXPRESSION; DIFFERENTIATION; INFLAMMATION; ANTIOXIDANT; CASPASE-14; CYTOKINES; IMPAIRS; MODEL
- 제목
- Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions
- 저자
- Oh, Yuri; Lim, Hye-Won; Kim, Kyunghoon; Lim, Chang-Jin
- 발행일
- 2016
- 유형
- Article
- 권
- 80
- 호
- 11
- 페이지
- 2165 ~ 2167