Stem cell engineering: limitation, alternatives, and insight

  • Lim, Jeong Mook
  • Lee, Myungook
  • Lee, Eun Ju
  • Gong, Seung Pyo
  • Lee, Seung Tae
Citations

WEB OF SCIENCE

14
Citations

SCOPUS

16

초록

The 21st century will see improvements in the quality of human life. The development of new therapeutic technologies will prevent prevalent diseases and enable recovery from currently incurable diseases. The development of cell and tissue replacement therapies using stem cells and their progenitors will accelerate the development of causative treatments. The effort expended thus far in developing cell therapies has revealed many technical limitations. Thus, we must explore conceptual changes in the feasibility of stem cell therapy. This paper introduces the current limitations to stem cell engineering and ways to overcome these limitations, which will provide new insight into their clinical application.

키워드

stern cellslimitationtissue-derivedcell nichecell transformation modelNUCLEAR TRANSFERSTROMAL CELLSSOMATIC-CELLSIN-VITROPLURIPOTENCYLINESDIFFERENTIATIONGERMLINE
제목
Stem cell engineering: limitation, alternatives, and insight
저자
Lim, Jeong MookLee, MyungookLee, Eun JuGong, Seung PyoLee, Seung Tae
DOI
10.1111/j.1749-6632.2011.06093.x
발행일
2011
유형
Article; Proceedings Paper
저널명
Annals of the New York Academy of Sciences
1229
페이지
89 ~ 98