Studies for component analysis and biological evaluation in Picrasma quassioides (D. Don) Benn. extracts

초록

This study investigates the chemical components and biological activities in Picrasma quassioides (D. Don) Benn. extracts for the purpose of developing natural pharmaceutical products. The proximate components in Picrasma quassioides (D. Don) Benn. extracts were 81.56% of carbohydrate, 5.80% of crude fat, 7.75% of crude protein, and 2.07% of crude ash. Calcium was the most predominant mineral and followed phosphorus, potassium, sodium, and magnesium, in a decreasing order. The content of the unsaturated fatty acids, such as oleic acid, linoleic acid, and linolenic acid, was find to be higher than those of saturated fatty acids. Water and methanol extract exhibited antioxidative activity with IC<inf>50</inf> of 128 μg/ml and 144 μg/ ml, respectively, suggesting that the extracts are the major biological component in Picrasma quassioides (D. Don) Benn. extracts. The α-glucosidase inhibitory activity showed that methanol and water extract were the high inhibitory activity. Considering these results, water extracts of Picrasma quassioides (D. Don) Benn. showed the possibility that they can be used as a new material for natural pharmaceutical products.

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