Evaluation of clinical usefulness of reference interval of some selected hematological parameters in canine blood

초록

To estimate the source of variance components for some hematological parameters and assessthe utility of the conventional population-based reference interval, this study computed index ofindividuality for blood samples, which were from 13 dogs drawn once weekly for 4 consecutive weeks.were greater than within-dog variation. Except for the parameters RBC and MCHC the index ofindividuality was <1.4. The low reliability coefficient and high index of individuality of ≤0.8 were foundfor the majority of hematological parameters. In practical term, the present study indicated that use ofhemogram profiles alone in the evaluating clinical state of a single patient should be avoided becauseof their physiological or natural random variations, and that comparing a single measurement on theinsensitive to detect any significant changes in the blood components of that particular dog. A singlemeasurement may not characterize an individuals average concentration of the parameters even short-term period.

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