Quality of safety reporting for complementary and alternative therapies for dysmenorrhea

초록

Objectives: This study assessed the quality of safety reporting in complementary and alternative therapies randomized controlled trials for primary dysmenorrhea. Methods: Methodologic systematic review of randomized controlled trials published until August 25, 2019 without language restrictions. The adequacies of safety reporting are reported as frequencies and percentages and their predictors were analyzed by multiple least-squares and logistic regressions. Results: Thirty-nine trials were included in this review. Of 39 trials, 56% (22/39) reported that no harms were observed. Of the predictor variables, the percentage of words reporting safety in the body section of text increased significantly with sample sizes (effect size 0.14, 95% confidence interval 0.01-0.26, p = .041). Conclusions: No harms of included trials were well-reported in complementary and alternative therapy journals. These findings will serve as sound guidance to assess the quality of safety reporting in further complementary and alternative therapies for primary dysmenorrhea.

키워드