Mushroom-Derived Bioactive Molecules as Immunotherapeutic Agents: A Review

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WEB OF SCIENCE

57
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71

초록

Mushrooms with enhanced medicinal properties focus on finding such compounds that could modulate the human body's immune systems. Mushrooms have antimicrobial, antidiabetic, antiviral, hepatoprotective, antitumor, and immunomodulatory properties due to the presence of various bioactive components. beta-glucans are the major constituent of the mushroom cell wall and play a significant role in their biological activity. This review described the techniques used in the extraction of the active ingredients from the mushroom. We highlighted the structure of the bioactive polysaccharides present in the mushrooms. Therapeutic applications of different mushrooms were also described. It is interesting to note that mushrooms have the potential sources of many bioactive products that can regulate immunity. Thus, the development of functional medicinal food based on the mushroom is vital for human welfare.

키워드

mushroom; antimicrobial; immunomodulatory; β -glucan; and functional food; MAITAKE GRIFOLA-FRONDOSA; FUNGAL IMMUNOMODULATORY PROTEIN; ANTITUMOR NATURAL-PRODUCT; AGARICUS-BLAZEI MURILL; STRUCTURAL-CHARACTERIZATION; TUMOR-BEARING; BETA-GLUCAN; MEDICINAL MUSHROOMS; CYTOKINE PRODUCTION; CORDYCEPS-SINENSIS
제목
Mushroom-Derived Bioactive Molecules as Immunotherapeutic Agents: A Review
저자
Patel, Dinesh K.; Dutta, Sayan Deb; Ganguly, Keya; Cho, Seong-Jun; Lim, Ki-Taek
DOI
10.3390/molecules26051359
발행일
2021-03
유형
Review
저널명
Molecules
권
26
호
5