Biological activities of solvent extracts from leaves of Aceriphyllum rossii

초록

In this study, the bioactivities of ethanol (EEAR) and water extract (WEAR) from the leaf of Aceriphyllum rossii were investigated. In the anti-oxidative activity, IC <inf>50</inf> of DPPH radical scavenging activity was respectively 549.86 and 62.14 μg/mL by EEAR and WEAR. Anti-inflammatory activity of EEAR and WEAR has been evaluated on inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) release by the macrophage RAW 264.7 cells. EEAR and WEAR inhibited inflammatory by 5.58 and 16.85% in 10 mg/mL, respectively. In the anti-diabetic activity, IC50 of α-glucosidase inhibitory activity was 5.62 and 425.63 μg/mL by EEAR and WEAR. IC <inf>50</inf> of α-amylase inhibitory activity of EEAR and WEAR was 4,623.87 and over 10,000 μg/mL, respectively. In the anti-obesity, all lipase inhibitory activity (IC <inf>50</inf>) of EEAR and WEAR was up 10,000 μg/mL. Finally, EEAR and WEAR exhibited anti-oxidative and anti-diabetic activity. It suggests that Aceriphyllum rossii could be potentially used as a resource of bioactive materials for health functional foods.

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