갯방풍 지상부 용매 분획물의 비표적 대사체 프로파일링 및 항산화 활성

초록

Background: The soft petiole of the Glehnia littoralis shoot is used as a raw material for food. It contains specific ingredients such as polyacetylene and coumarin. However, basic research consid ering their safety verification, efficacy, and ingredient identification is needed. Methods and Results: In this study, GC/MS compound profiling and LC/UVD were performed to evaluate the antioxidant activity of G. littoralis shoot extract fractions, and to identify the com pounds contained therein. Total phenol and flavonoid content as well as antioxidant activity were maximum in the ethyl acetate layer, and a significant correlation was confirmed between total phe nol content and antioxidant activity. GC/MS compound profiling, revealed a total of more than 40 compounds, and active ingredients such as coumarin-based phellopterin unique to G. littoralis and polyacetylene-based falcarinol (panaxinol) were qualitatively analyzed. The highest coumarin con tent was found in the ethyl acetate layer. Conclusions: In this study, the antioxidant activity and compounds contained in the shoot (soft pet iole) fractions of G. littoralis were confirmed. These basic data may contribute to expanding the material value of G. littoralis in the future.

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