Unmasked Acyl Anion Equivalent from Acid Chloride with Indium: Reversed-Polarity Synthesis of Unsymmetric Aryl Aryl and Alkenyl Aryl Ketone through Palladium-Catalyzed Cross-Coupling Reaction

Lee, Dohyung; Ryu, Taekyu; Park, Youngchul; Lee, Phil Ho

doi:10.1021/ol500003g

상세 보기

Unmasked Acyl Anion Equivalent from Acid Chloride with Indium: Reversed-Polarity Synthesis of Unsymmetric Aryl Aryl and Alkenyl Aryl Ketone through Palladium-Catalyzed Cross-Coupling Reaction

Lee, Dohyung;
Ryu, Taekyu;
Park, Youngchul;
Lee, Phil Ho

Citations

WEB OF SCIENCE

45

Citations

SCOPUS

44

초록

A reversed-polarity synthetic method of a range of unsymmetric aryl aryl and alkenyl aryl ketones has been developed through Pd-catalyzed cross-coupling reaction of acylindium reagents generated in situ from easily available acid chlorides and indium with various electrophiles such as aryl iodide and triflate and alkenyl triflate.

키워드

ELECTRON-RICH OLEFINS; CARBON BOND FORMATION; GENERATED IN-SITU; DIRECT ACYLATION; ACYLZIRCONOCENE CHLORIDE; COOPERATIVE CATALYSIS; ORGANOINDIUM REAGENTS; CONVENIENT ROUTE; ALLYLIC ESTERS; HECK ARYLATION

제목: Unmasked Acyl Anion Equivalent from Acid Chloride with Indium: Reversed-Polarity Synthesis of Unsymmetric Aryl Aryl and Alkenyl Aryl Ketone through Palladium-Catalyzed Cross-Coupling Reaction

저자: Lee, Dohyung; Ryu, Taekyu; Park, Youngchul; Lee, Phil Ho

DOI: 10.1021/ol500003g

발행일: 2014-02-21

유형: Article

저널명: Organic Letters

권: 16

호: 4

페이지: 1144 ~ 1147