Synthesis of Pyrroles from Terminal Alkynes, N-Sulfonyl Azides, and Alkenyl Alkyl Ethers through 1-Sulfonyl-1,2,3-triazoles

Kim, Cheol-Eui; Park, Sangjune; Eom, Dahan; Seo, Boram; Lee, Phil Ho

doi:10.1021/ol500718s

상세 보기

Synthesis of Pyrroles from Terminal Alkynes, N-Sulfonyl Azides, and Alkenyl Alkyl Ethers through 1-Sulfonyl-1,2,3-triazoles

Kim, Cheol-Eui;
Park, Sangjune;
Eom, Dahan;
Seo, Boram;
Lee, Phil Ho

Citations

WEB OF SCIENCE

117

Citations

SCOPUS

125

초록

A method for synthesis of substituted pyrroles has been developed. 1-Sulfonyl-1,2,3-triazoles generated from terminal alkynes gave alpha-imino rhodium carbene complexes, which when reacted with alkenyl alkyl ethers afforded substituted pyrroles. The method can be efficiently applied to a one-pot sequential reaction starting from terminal alkynes.

키워드

CATALYZED TRANSANNULATION; STEREOSELECTIVE-SYNTHESIS; ANNULATION; TRIAZOLES; REACTIVITY; INDOLES; COPPER; FURANS

제목: Synthesis of Pyrroles from Terminal Alkynes, N-Sulfonyl Azides, and Alkenyl Alkyl Ethers through 1-Sulfonyl-1,2,3-triazoles

저자: Kim, Cheol-Eui; Park, Sangjune; Eom, Dahan; Seo, Boram; Lee, Phil Ho

DOI: 10.1021/ol500718s

발행일: 2014-04-04

유형: Article

저널명: Organic Letters

권: 16

호: 7

페이지: 1900 ~ 1903