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초록
In this study a biosensor was developed by using Drosophila cells expressing a gustatory receptor Gr5a and an ion sensitive field effect transistors (ISFETs) sensor device, which demonstrated significant compatibility with the Drosophila cells expressing Gr5a and their response to sugar. These results suggested that the newly developed cell based biosensor has a potential as a simple and easy screening device for Alzheimer’s, disease in the future.
키워드
Alzheimer’s disease (AD); Non-invasive sampling; Sugars as AD biomarker candidate; Cell based biosensor; Drosophila; ISFET; Medical diagnostic device
- 제목
- 알츠하이머 진단을 위한 당성분에 민감한 초파리 세포기반 ISFET센서개발
- 제목 (타언어)
- Development of Sugar Sensitive Drosophila Cell based ISFET Sensor for Alzheimer’s Disease Diagnosis
- 저자
- 임정옥; 유준부; 권재영; 변형기; 허증수; 조원주
- 발행일
- 2013-07
- 유형
- Y
- 저널명
- 센서학회지
- 권
- 22
- 호
- 4
- 페이지
- 281 ~ 285