더덕 잎, 줄기, 뿌리 부위의 Triterpenoid 사포닌 함량

초록

Codonopsis lanceolata (Campanulaceae) has been used in traditional medicines, as its roots contain severalkinds of 3,28-bidesmosidic triterpenoid saponin with high medicinal values. In this study, we induced hairy root-derivedtransgenic plants of C. lanceolata and analyzed triterpenoid saponins from the leaf, stem and root. Transgenic plants wereregenerated from the hairy roots via somatic embryogenesis. The saponins are lancemaside A, B and E, foetidissimoside A,and aster saponin Hb. Transgenic plants contained richer triterpenoids saponin than wild-type plants. Major saponin lancemasideA was the most abundant saponin in the stem from transgenic-plant, 4.76 ㎎·1−1 dry stem. These results suggest thattransgenic plants of C. lanceolata could be used as medicinal materials for the production of triterpene saponins.

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