Can CRISPRized crops save the global food supply?

초록

The increase in the human population and climate change witnessed worldwide makes the production of high-yielding fruit crops with developed adaptation to the environment a critical issue for which requirement is unlikely to be met through traditional breeding. RNA interference (RNAi) and the clustered regularly interspaced short palindromic repeat (CRISPR) method have emerged in recent years as effective methods for targeted mutagenesis including single-base substitution, multiplex gene editing, gene knockouts, and plant gene transcription regulation. Thus genome editing dependent on CRISPR has indicated an incredible potential for crop improvement and plant protection but is still in its outset stage. Both RNAi and CRISPR are expected to gain popularity, mainly focused on genome editing and speed breeding. The presented techniques could become basic protocols for acquiring plants with exceptional alluring attributes and assisting with accomplishing our zero-hunger targets internationally. © 2021 Elsevier Inc. All rights reserved.

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