상세 보기
A Formal Total Synthesis of Dysiherbaine and Neodysiherbaine A
- Lee, Hee-Yoon;
- Lee, Sang-Shin;
- Kim, Hoon Seok;
- Lee, Kang Mun
Citations
WEB OF SCIENCE
14Citations
SCOPUS
16초록
A domino olefin metathesis reaction of 1-alkyl-3-(allyloxy)-7-oxabicyclo[2.2.1]hept-5-enes 7 produced the fused bis(oxacyclic) structure for dysiherbaine and neodysiherbaine A (i.e., 6b) with the complete control of the relative stereochemistry at the quaternary carbon center and the ring junction of the dysiherbaine core skeleton. A formal total synthesis of dysiherbaine and neodysiherbaine A was achieved from 6b.
키워드
Total synthesis; Natural products; Oxygen heterocycles; Cycloaddition; Domino reactions; Chiral resolution; STEREOCONTROLLED TOTAL-SYNTHESIS; BIOLOGICAL EVALUATION; AMINO-ACID; ANALOGS; FURAN; DECARBOXYLATION; METATHESIS; ESTERS
- 제목
- A Formal Total Synthesis of Dysiherbaine and Neodysiherbaine A
- 저자
- Lee, Hee-Yoon; Lee, Sang-Shin; Kim, Hoon Seok; Lee, Kang Mun
- 발행일
- 2012-08
- 유형
- Article
- 권
- 2012
- 호
- 22
- 페이지
- 4192 ~ 4199