Metal-free, Bronsted acid-mediated synthesis of coumarin derivatives from phenols and propiolic acids

초록

A novel synthesis of coumarin derivatives by Bronsted acid-mediated condensation and intramolecular cyclization of phenols and propiolic acids was reported. This transformation requires the use of TfOH in place of a conventional metal mediator, and it occurs under mild conditions and provides rapid access to coumarin derivatives in good yields. (C) 2016 Published by Elsevier Ltd.

키워드