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Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells
- Choi Ingyu;
- Kim, Kyungjong;
- Kim, Youngmi;
- Park, Mi-Jin;
- Lee, Yun-Sil;
- ... Jeoung, Dooil
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6초록
Allergic inflammation results from stimulation of beta-hexosaminidase secretion, increased calcium influx, and activation of MAPK pathways. Some fractions of Chamaecyparis obtusa decreased secretion of beta-hexosaminidase, calcium influx, ROS, and phosphorylation of ERK. These results suggest that Chamaecyparis obtusa would be valuable for development of allergy therapeutics.
키워드
allergic inflammation; beta-hexosaminidase; calcium influx; Chamaecyparis obtusa; ERK; reactive oxygen species; TEA TREE OIL; MAST-CELLS; ASTHMA MODEL; RELEASE; ANTIGEN; GENERATION; MICE
- 제목
- Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells
- 저자
- Choi Ingyu; Kim, Kyungjong; Kim, Youngmi; Park, Mi-Jin; Lee, Yun-Sil; Jeoung, Dooil
- 발행일
- 2006-11
- 유형
- Article
- 권
- 16
- 호
- 11
- 페이지
- 1747 ~ 1752