Surgical management of vesicoureteral reflux with recurrent urinary tract infection after renal transplantation in a dog

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초록

CASE DESCRIPTION A 3-year-old male Cocker Spaniel renal transplant recipient was readmitted 39 weeks after transplantation because of acute clinical signs of pollakiuria, intermittent vomiting, decreased appetite, lethargy, and mild fever. CLINICAL FINDINGS Hydronephrosis and hydroureter were observed with ultrasonography and contrast cystography, and a diagnosis of vesicoureteral reflux (VUR) was made. Urinary tract infection (UTI) caused by Escherichia coli was also diagnosed on the basis of results of urine culture. TREATMENTAND OUTCOME Despite treatment of the UTI with an appropriate antimicrobial for 6 weeks,the VUR persisted and the UTI recurred 9 weeks after cessation of antimicrobial treatment. Therefore, surgical correction by means of revision extravesicular ureteroneocytostomy was performed. Both VUR and hydronephrosis resolved after surgery. No recurrences of clinical signs of urinary tract complications were observed during the subsequent 22-month follow-up period. CLINICAL RELEVANCE Results suggested that ureteral reimplantation with an extravesicular technique incorporating a long submucosal tunnel may be an effective treatment for VUR when medical management fails in canine renal transplant recipients with recurrent UTIs.

키워드

KIDNEY-TRANSPLANTATIONCLINICAL-SIGNIFICANCERISK-FACTORSCYCLOSPORINETOLERANCECHILDRENIMMUNOSUPPRESSIONCOMBINATIONFREQUENCYMODEL
제목
Surgical management of vesicoureteral reflux with recurrent urinary tract infection after renal transplantation in a dog
저자
Park, Kyung-MeeNam, Hyun-SukHussein, Kamal HanyWoo, Heung-Myong
DOI
10.2460/javma.248.3.309
발행일
2016-02-01
유형
Article
저널명
Journal of the American Veterinary Medical Association
248
3
페이지
309 ~ 314