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Regioselective synthesis of 4-alkylpyridines from pyridine and aldehydes via dipole reversal process of 1,4-dihydropyridine phosphonate
- Lee, PH;
- Lee, K;
- Shim, JH;
- Lee, SG;
- Kim, S
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5초록
4-Alkylation of pyridine has been accomplished by the reaction of ylides, derivated from 1,4-dihydropyridine phosphonate via phosphonloalkoxy-carbonylation of pyridine with aldehydes and subsequent elimination of diisopropyl phosphate followed by aromatization with potassium tert-butoxide.
키워드
1-ACYLPYRIDINIUM SALTS; GRIGNARD-REAGENTS; ASYMMETRIC-SYNTHESIS; DERIVATIVES; CHLORIDE
- 제목
- Regioselective synthesis of 4-alkylpyridines from pyridine and aldehydes via dipole reversal process of 1,4-dihydropyridine phosphonate
- 저자
- Lee, PH; Lee, K; Shim, JH; Lee, SG; Kim, S
- 발행일
- 2006-02-01
- 유형
- Article
- 저널명
- Heterocycles
- 권
- 67
- 호
- 2
- 페이지
- 777 ~ +