개 디스템퍼 바이러스에 선택적인 예방접종 및 그 계획에 대한 자견의 혈청학적 반응

초록

We examined the responses of PBMCs to house dust mite (HDM) allergen in atopic and healthy, non-atopicdogs to identify differences in lymphocyte reactivity that might reflect the immunologic status of atopic dermatitis. Thirteenwas significantly higher in the atopic dogs than that in healthy, non-atopic dogs insensitive to the allergen (P = 0.007).The proliferative responses were positively correlated with the level of HDM-specific IgE in serum (P = 0.035), and werethereby confirmed to reflect the activity of lymphocytes competent to promote IgE production. These results suggestthat HDM-specific lymphocytes were present in peripheral blood and played a role in the pathogenesis of canine atopicdermatitis.

키워드