Antioxidative properties of ginsenoside Ro against UV-B-induced oxidative stress in human dermal fibroblasts

  • Kang, Hyun Ji
  • Oh, Yuri
  • Lee, Sihyeong
  • Ryu, In Wang
  • Kim, Kyunghoon
  • 외 1명
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초록

Ginsenoside Ro (Ro), an oleanolic acid-type ginsenoside, exhibited suppressive activities on reactive oxygen species (ROS) and matrix metalloproteinase-2 (MMP-2) elevation in UV-B-irradiated fibroblasts. Ro could overcome the reduction of the total glutathione (GSH) contents in UV-B-irradiated fibroblasts. Ro could not interfere with cell viabilities in UV-B-irradiated fibroblasts. Collectively, Ro possesses a potential skin anti-photoaging property against UV-B radiation in fibroblasts.

키워드

ginsenoside RoUV-B radiationoxidative stressreactive oxygen speciesglutathioneGLUTATHIONEQUANTITIES
제목
Antioxidative properties of ginsenoside Ro against UV-B-induced oxidative stress in human dermal fibroblasts
저자
Kang, Hyun JiOh, YuriLee, SihyeongRyu, In WangKim, KyunghoonLim, Chang-Jin
DOI
10.1080/09168451.2015.1065170
발행일
2015-12-02
유형
Article
저널명
Bioscience, Biotechnology and Biochemistry
79
12
페이지
2018 ~ 2021