Complexation-responsive monoolein cubic phase containing extract of Bambusae Caulis in Taeniam

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초록

Monoolein (MO) cubic phase (CP) containing Bambusae Caulis in Taeniam extract (BCT), hydrophobically modified alginate (HmAlg), and hydrophobically modified gelatin (HmGel) was prepared by a melt and hydration method. On the TEM micrographs of CP, water channels and MO bilayers were found. The phase transition temperature of MO CP was about 65.3 degrees C and it deceased by the inclusion of the additives. The release of 4-hydroxybenzaldehyde from CP was markedly suppressed at pH 4.5 but not at pH 5.5 and pH 7.4. The complex coacervate of HmGel and HmAlg was thought to suppress the release in the acidic condition.

키워드

4-HydroxybenzaldehydeBambusae Caulis in Taeniamcomplexationcubic phasemonooleinLIQUID-CRYSTALLINE PHASESDRUGSTABILITYRELEASESYSTEM
제목
Complexation-responsive monoolein cubic phase containing extract of Bambusae Caulis in Taeniam
저자
Park, Seok HoKim, Jin-Chul
DOI
10.1080/00914037.2018.1539986
발행일
2020-01-02
유형
Article
저널명
International Journal of Polymeric Materials and Polymeric Biomaterials
69
1
페이지
44 ~ 52