Ionic liquid incorporated polystyrene resin for solid-phase peptide synthesis

Cho, Hong-Jun; Lee, Sang-Myung; Jung, Sungwon; Lee, Tae-Kyung; Yoon, Hyo-Jin; Lee, Yoon-Sik

doi:10.1016/j.tetlet.2011.01.067

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Ionic liquid incorporated polystyrene resin for solid-phase peptide synthesis

Cho, Hong-Jun;
Lee, Sang-Myung;
Jung, Sungwon;
Lee, Tae-Kyung;
Yoon, Hyo-Jin;
외 1명

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9

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SCOPUS

10

초록

Ionic liquid (IL) resins with an ionic liquid environment on solid support were prepared by immobilizing ionic liquid spacers on polystyrene (PS) resin. The properties of IL resins were dramatically changed as the anions of IL were exchanged. The performance of IL resins for solid-phase peptide synthesis (SPPS) was evaluated by measuring coupling kinetics of the first amino acid and synthesizing several peptides on IL resins. (c) 2011 Elsevier Ltd. All rights reserved.

키워드

Ionic liquid; Anion exchange; Ionic liquid resin; Solid-phase peptide synthesis (SPPS); POLYMER; CATALYSTS; PALLADIUM

제목: Ionic liquid incorporated polystyrene resin for solid-phase peptide synthesis

저자: Cho, Hong-Jun; Lee, Sang-Myung; Jung, Sungwon; Lee, Tae-Kyung; Yoon, Hyo-Jin; Lee, Yoon-Sik

DOI: 10.1016/j.tetlet.2011.01.067

발행일: 2011-03-30

유형: Article

저널명: Tetrahedron Letters

권: 52

호: 13

페이지: 1459 ~ 1461