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초록
Four new megastigmane glycosides, named gusanlungionosides A-D (1-4), together with 10 known compounds (5-14), were isolated from the stems of Arcangelisia gusanlung. The structures and absolute configurations of 1-4 were elucidated by comprehensive analysis of their NMR and CD data. Compounds 1-4 exhibited strong inhibitory effects not only on the mushroom tyrosinase activity in vitro but also on melanogenesis in cells.
키워드
MEGASTIGMANE GLYCOSIDES; ACANGELISIA-GUSANLUNG; ALKALOIDS; GLUCOSIDES; MELANOGENESIS; MELANOMA; L.
- 제목
- Gusanlungionosides A-D, Potential Tyrosinase Inhibitors from Arcangelisia gusanlung
- 저자
- Yu, Ling-Ling; Hu, Wei-Cheng; Ding, Gang; Li, Rong-Tao; Wei, Jian-He; Zou, Zhong-Mei; Wang, Myeong-Hyeon
- 발행일
- 2011-05
- 유형
- Article
- 권
- 74
- 호
- 5
- 페이지
- 1009 ~ 1014