Two-dimensional SERS encoding method for on-bead peptide sequencing in high-throughput bioanalysis

  • Jeong, Sinyoung
  • Kang, Homan
  • Cha, Myeong Geun
  • Lee, Sung Gun
  • Kim, Jaehi
  • ... Chang, Hyejin
  • 외 2명
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초록

We developed a ready-to-read on-bead peptide encoding method for high-throughput screening bioassays. With two-dimensional surface-enhanced Raman scattering nano-identifiers (2D-SERS IDs) which are concurrently labelled with two SERS codes (coupling steps and kinds of amino acid), we could possibly generate more than 10 trillion codes with only 30 Raman label compounds.

키워드

ENHANCED RAMAN-SCATTERINGMICROBEADSLIBRARYSYSTEM
제목
Two-dimensional SERS encoding method for on-bead peptide sequencing in high-throughput bioanalysis
저자
Jeong, SinyoungKang, HomanCha, Myeong GeunLee, Sung GunKim, JaehiChang, HyejinLee, Yoon-SikJeong, Dae Hong
DOI
10.1039/c8cc10224d
발행일
2019-03-04
유형
Article
저널명
Chemical Communications
55
18
페이지
2700 ~ 2703