Antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium from a Jeju water concentrate

  • Yun, Ji-Hyun; 
  • Park, Sung-Hwan; 
  • Choi, Goo-Hee; 
  • Park, In-Jae; 
  • Lee, Jin-Ha; 
  • ... Lee, Ok-Hwan; 
  • 외 3명
Citations

WEB OF SCIENCE

9
Citations

SCOPUS

6

초록

The purpose of this study was to determine the antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium (BECV). The BECV was prepared following nutriculture of B. napus with a Jeju water vanadium concentrate for 7day. The BECV was administered to db/db mice for 8weeks at different dosages (0.028, 0.14, and 0.7g/kg; as vanadium concentration in BECV). After 8weeks, the BECV results showed mouse blood glucose concentrations to significantly decrease, in a dose-dependent manner, compared with the results for control mice. In addition, the concentrations of triglyceride, total cholesterol, and glycated hemoglobin were significantly lower after 8weeks of administration of 0.7g/kg BECV. Therefore, the BECV may have protective effects against type 2 diabetes.

키워드

Vanadium; Brassica napus extract; Antidiabetic effect; db; db mouse; DIABETIC RATS RESTORES; GLUCOSE-HOMEOSTASIS; VANADATE TREATMENT; BLOOD-GLUCOSE; HYPERGLYCEMIA; IMPROVEMENT; METFORMIN; LIVER
제목
Antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium from a Jeju water concentrate
저자
Yun, Ji-Hyun; Park, Sung-Hwan; Choi, Goo-Hee; Park, In-Jae; Lee, Jin-Ha; Lee, Ok-Hwan; Kim, Jung-Hyon; Seo, Yun-Hee; Cho, Ju-Hyun
DOI
10.1007/s10068-018-0436-8
발행일
2019-02
유형
Article
저널명
Food Science and Biotechnology
권
28
호
1
페이지
209 ~ 214