Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing

  • Singh, Atul P.; 
  • Lee, Kang Mun; 
  • Murale, Dhiraj P.; 
  • Jun, Taehong; 
  • Liew, Hyunjeong; 
  • 외 2명
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초록

Bis-arylsulfide BODIPY systems were prepared and studied for multiple O-atom sensing (at 522 nm); 2- and 3-atom loading was optimal (50-fold, "turn on"). Neuronal studies showed greater H2O2 sensitivity than 2',7'-dichlorofluorescein diacetate. The novel 1,3,6-trimethyl BODIPY formed as a biproduct under Lindsey conditions.

키워드

BORON-DIPYRROMETHENE DYES; HYDROGEN-PEROXIDE; LIVING CELLS; PROBES; CHEMISTRY; BIOLOGY; BINDING
제목
Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing
저자
Singh, Atul P.; Lee, Kang Mun; Murale, Dhiraj P.; Jun, Taehong; Liew, Hyunjeong; Suh, Yoo-Hun; Churchill, David G.
DOI
10.1039/c2cc33076h
발행일
2012
유형
Article
저널명
Chemical Communications
권
48
호
58
페이지
7298 ~ 7300