상세 보기
Calpain inhibitory flavonoids isolated from Orostachys japonicus
- Ma, Choong Je;
- Jung, Won Joo;
- Lee, Ki Yong;
- Kim, Young Choong;
- Sung, Sang Hyun
Citations
WEB OF SCIENCE
32Citations
SCOPUS
35초록
The n-butanol (n-BuOH) fraction of Orostachys japonicus A. Berger (Crassulaceae) significantly inhibited calpain activity. Through the activity-guided isolation from the n-BuOH fraction, herbacetin 8-O-alpha-D-ribopyranoside (1), kaempferol (2), quercetin (3), afzelin (4), astragalin (5), isoquercetin (6) and quercitrin (7) were obtained. Their structures were determined by spectroscopic techniques. Among them, compound 3 and 5 had significant calpain inhibitory activities.
키워드
Orostachys japonicus; flavonoid; calpain; neuroprotection; inhibition; QUERCETIN
- 제목
- Calpain inhibitory flavonoids isolated from Orostachys japonicus
- 저자
- Ma, Choong Je; Jung, Won Joo; Lee, Ki Yong; Kim, Young Choong; Sung, Sang Hyun
- 발행일
- 2009
- 유형
- Article
- 권
- 24
- 호
- 3
- 페이지
- 676 ~ 679
- 언어
- ENG
- 출판사
- TAYLOR & FRANCIS LTD
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- E 1475-6374
P 1475-6366